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A Journal on Internal Medicine


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Panminerva Medica 2005 March;47(1):61-4

language: English

Association between Crohn’s disease and Conn’s syndrome. A report of two cases

Astegiano M., Bresso F., Demarchi B., Sapone N., Novero D. 2, Palestro G. 2, Resegotti A. 3, Pellicano R.,. Rizzetto M.

1 Unit of Gastroenterology and Hepatology S. Giovanni Battista Hospital, Turin, Italy
2 Unit of Pathology S. Giovanni Battista Hospital, Turin, Italy
3 Unit of Surgery S. Giovanni Battista Hospital, Turin, Italy


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The natural history of Crohn’s disease (CD) is characterised by periods of remission followed by phases of flares. Persistent or intractable diarrhoea may be associated with ileal disease or arise following ileal resection, resulting in potassium depletion. Medical therapy with steroids presents troublesome side-effects (e.g. hypertension). Conn’s syndrome, caused by unilateral aldosterone-producing adenoma, is characterised by clinical features including hypokalaemia and hypertension. Thus, CD and Conn’s syndrome may have an overlap of manifestations, and up to now, the simultaneous occurrence of these conditions has not been described. We report here 2 cases of association between CD and Conn’s syndrome.

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