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A Journal on Internal Medicine

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Panminerva Medica 2005 March;47(1):19-30

language: English

The role of peritoneal dialysis in renal replacement therapy: an update on medical aspects

Yao Q. 1,2, Wang X. 1,3, Chung S. H. 1,4, Pecoits-Filho R. 1,5, Stenvinkel P. 1, Wang T. 1,3, Heimbürger O. 1, Lindholm B. 1

1 Divisions of Baxter Novum and Renal Medicine Department of Clinical Sciences Karolinska Institutet Huddinge University Hospital, Stockholm, Sweden
2 Renal Division, Renji Hospital affiliated to Shanghai Second Medical University, Shanghai, P. R. China
3 Institute of Nephrology, First Hospital Peking University, Beijing, P. R. China
4 Hyonam Kidney Laboratory Soon Chun Hyang University, Seoul, Korea
5 Center for Health Biological Sciences Pontifícia Universidade Católica do Paraná, Curitiba, Brazil


In this brief review, we discuss various medical factors that are of importance for the role of peritoneal dialysis (PD) in renal replacement therapy (RRT), whereas the complex role of non medical factors will only be mentioned briefly. The aim of any RRT, including hemodialysis, PD and renal transplantation, is to normalize the volume and composition of the body fluids, to remove uremic toxins, and to improve clinical outcome. In the following, we will focus on adequacy, preservation of residual renal function, fluid balance, infections, nutrition, cardiovascular disease and systemic inflammation in PD as these factors are strong predictors of clinical outcome in end stage renal disease patients.

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