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Panminerva Medica 2002 September;44(3):271-4

language: English

Spontaneous regression and recurrence of primary low-grade B-cell gastric lymphoma on the gastric stump 15 and 20 years after gastroresection

Pentimone F., Moncini C., Pastine F., Gerini A., Lucchesi Q.

Department of Internal Medicine, Section of Geriatrics, University of Pisa, Pisa, Italy


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The recur­rence of pri­mary gas­tric lym­phoma (PGL) on the gas­tric ­stump ­after gas­tror­e­sec­tion is ­rare. We ­describe the ­case of an 84-­year-old man who had recur­rences 15 and 20 ­years ­after a Billroth I gas­trec­tomy. The con­cor­dance of the ­three gas­tric biop­sies ­showing a low ­grade B-­cell lym­pho­cytic lym­phoma of the ­mucosa-asso­ciated ­tissue, dem­on­strated the recur­rence of the dis­ease. The ­patient has ser­o­log­ical evi­dence of Helicobacter ­pylori infec­tion but the erad­i­ca­tion ­therapy had no ­effect on the evo­lu­tion of the dis­ease. The ­case sug­gests ­that PGL is ­really a par­tic­ular ­entity in the non-Hodgkin’s lym­phoma ­group, char­ac­ter­ized by a ­long spon­ta­neous nat­ural his­tory, ­with ­long ­lasting spon­ta­neous remis­sions and recur­rences.

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