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Panminerva Medica 2001 December;43(4):307-10

language: English

Changes in splenoportal axis calibre and flow in a patient affected by hereditary angioedema

Campanile E., Scuderi R., Ierna D., Neri S.

From the Department of Internal and Emergency Medicine S. Marta Hospital, University of Catania, Catania, Italy


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The authors ­describe a ­case of hered­i­tary angioe­de­ma char­ac­ter­ised by abdom­i­nal ­pain accom­pa­nied by ­ascites. Ultrasound (US) exam­ina­tion per­formed ­after ­acute abdom­i­nal ­attack ­implied the pres­ence of ­increased splen­o­por­tal ­axis cal­i­bre and ­reduced ­blood ­flow. According to the ­authors, ­this may con­firm the path­o­gen­ic ­role of C1-inhib­i­tor defi­cien­cy ­induced oede­ma ­that is ­capable of creat­ing ­major hae­mod­y­nam­ic involve­ment ­also of abdom­i­nal ves­sels. US find­ings of tran­sient appear­ance, espe­cial­ly relat­ed to the spe­cif­ic treat­ment, may ­help phy­si­cians ­make ear­ly diag­no­sis and ­avoid dan­ger­ous inva­sive pro­ce­dures result­ing ­from incor­rect diag­no­sis of ­acute abdo­men.

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