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Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,6
Online ISSN 1827-1898
Brovedani P., Masi G.
From the Division of Child Neurology and Psychiatry University of the Study, Pisa IRCCS Stella Maris, Calambrone, Pisa
The interplay between neurologic, neuropsychologic and psychiatric features makes Tourette’s syndrome (TS) a paradigmatic model for neuropsychiatric disorders. The aim of this paper is to review this complex interplay of clinical features. After a survey of some epidemiological studies, the natural history of neurological, behavioral and psychological characteristics of the syndrome is described. The problem of high psychiatric comorbidity, firstly with obsessive-compulsive disorder and attention deficit-hyperactivity disorder, is discussed. Neuropsycholo-gical features of TS are considered, as they can negatively affect the quality of life of affected patients. Consi-derations on treatment, pharmacologic as well as educational and psychotherapeutic, conclude this review.