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A Journal on Internal Medicine

Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,6

Frequency: Quarterly

ISSN 0031-0808

Online ISSN 1827-1898


Panminerva Medica 1999 December;41(4):311-3


Bron­chi­al reac­tiv­ity in sub­jects ­with urti­car­ia

Anania A., Striglia E.

From the Depart­ment of Inter­nal Med­i­cine Sec­ond ­Chair of Inter­nal Med­i­cine (­Head: ­Prof. G. M. Mol­i­nat­ti) Turin Uni­ver­sity, Ita­ly

Back­ground. Res­pir­a­to­ry symp­toms (rhin­itis, asth­ma) accom­pa­ny ­some ­skin dis­eas­es ­with a prov­en immu­no­log­i­cal or aller­gic path­o­gen­e­sis where­as the immu­no­log­i­cal and aller­go­log­i­cal find­ings are some­times neg­a­tive in sub­jects ­with chron­ic urti­car­i­al ­skin symp­toms and no ­cause can be ­found. ­This ­paper ­explores the pos­sibil­ity of air­way inflam­ma­tion in cas­es of ­this ­kind.
Meth­ods. Non­spe­cif­ic bron­chos­tim­u­la­tion ­with methach­o­line was car­ried out in 12 sub­jects ­with a clin­i­cal his­to­ry of urti­car­ia and neg­a­tive immu­no­log­i­cal and aller­go­log­i­cal find­ings.
­Results. All sub­jects dis­played nor­mal bron­cho­reac­tiv­ity (mean PD20 1400 µg). The bron­chos­tim­u­la­tion ­test (eval­u­at­ed ­from the FEV1) was ­always neg­a­tive. In the con­trol ­group the ­mean PD20 was 720 µg.
Con­clu­sions. The ­fact ­that ­these ­eleven sub­jects did not dis­play bron­chi­al hyper­reac­tiv­ity sug­gests ­that mon­i­tor­ing of ­their res­pir­a­to­ry func­tion is not ­required.

language: English


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