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A Journal on Internal Medicine

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Panminerva Medica 1998 September;40(3):174-8

language: English

Laser-Doppler-flowmetry in pre­term new­borns dur­ing apne­ic ­events

Sabatino G., Chiarelli F.*, Angelozzi B., Verrotti A.*, Ramenghi L. A.

From the Department of Pediatrics-Neonatal Intensive Care Unit and * Pediatric Clinic «G. D'Annunzio» University, Chieti, Italy


Materials and meth­ods. We have stud­ied with Laser-Doppler-Flowmetry (LDF) Skin Blood Flow Perfusion (SBFP) dur­ing apne­ic ­events in 15 pre­term new­borns (mean GA 32.4 w; mean B.W. 1620). Eighty-four apne­ic epi­sodes were ana­lyzed and the ­results were gath­ered into two ­groups. Group 1 with SBFP belong­ing to pre­terms aged up to 5 days and Group 2 with SBFP ­records of some older new­borns (from 5th to 10th day of life). At first a ­decrease of LDF was often ­observed dur­ing apne­ic ­events.
Results. A sta­tis­ti­cal­ly sig­nif­i­cant dif­fer­ence ­between the two ­groups was noted con­sid­er­ing the SBFP per­cent­age reduc­tion, the hem­a­toc­rit and the time of appear­ance of the skin blood flow ­decrease. We also stud­ied the mean of all apne­ic SBFP reduc­tions in each of those new­borns (11/14) who had apne­ic ­events in both peri­ods, observ­ing a remark­able ­increase in mean SBFP reduc­tion when the new­borns were older than five days.
Conclusions. These dif­fer­enc­es can be ­caused by rhe­o­log­ic fac­tors such as high hem­a­toc­rit, less pro­nounced red cell deform­abil­ity and a sort of cold vasop­a­ral­y­sis more evi­dent in the first days of life. We think laser-Doppler-flowmetry be sug­gest­ed when the new­born is able to bet­ter con­trast the neg­a­tive ­effects of apnea, for exam­ple cen­tral­iz­ing the cir­cle in ­favour of vital ­organs.

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