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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery

Indexed/Abstracted in: EMBASE, Scopus




Otorinolaringologia 2013 September;63(3):111-21

language: English

State-of-the-art biomaterials in the nasal cavity: hemostats and spacers following sinus surgery

Cho K.-S. 1, Zajac A. E. 2, Rashan A. R. 3, Hwang P. H. 3, Nayak J. V. 3

1 Department of Otorhinolaryngology and Biomedical Research Institute Pusan National University School of Medicine Busan, South Korea;
2 Rosalind Franklin University of Medicine and Science North Chicago, IL, USA;
3 Department of Otolaryngology-Head and Neck Surgery Stanford University School of Medicine Stanford, CA, USA


The aim of this paper to review recent advances in biomaterials used as hemostats and spacers in the nose and to differentiate their effects on hemostasis, prevention of adhesions, and wound healing by evaluating their respective properties. Selective review of literature from query of multiple disparate database sources. Articles were selected for their relevance to the effects of biomaterials in the nose on hemostasis, prevention of synechiae/adhesions, and wound healing. Biomaterials have been extensively researched for many years, particularly in their modulation of wound healing, tissue regeneration, and drug delivery. When evaluating the suitability of various biomaterials following sinonasal surgery, their influence on wound healing should be given particular attention. The choice of biomaterials for packing or hemostasis will naturally be dependent on the preferences and experience of the surgeon, and the particular intraoperative findings and details of each patient scenario. When biomaterials are used following sinus surgery, judicious application of biomaterials in the nasal cavity may reduce the incidence of early postoperative bleeding and formation of synechiae/adhesions, and possibly promote healing of mucosa.

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