Home > Journals > Otorinolaringologia > Past Issues > Otorinolaringologia 2012 June;62(2) > Otorinolaringologia 2012 June;62(2):101-19

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

OTORINOLARINGOLOGIA

A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery


Indexed/Abstracted in: EMBASE, Scopus


eTOC

 

  OTITIS MEDIA


Otorinolaringologia 2012 June;62(2):101-19

language: English

Rational for immunotherapy treatment of otitis media with effusion

Hurst D. S.

Tufts University, Boston, MA, USA


PDF  


This review will examine the science that supports or refutes the possible value of using immunotherapy for the treatment of chronic middle ear disease. The role of allergy in chronic otitis media with effusion (OME) is controversial. New evidence from the fields of cellular biology and immunology now explain the basics of allergic reactions, and allow us to more accurately diagnose allergies and understand the allergic contribution to chronic inflammatory disease throughout the unified airway, including the middle ear. This review will examine the epidemiologic, methodological and immunologic studies of allergic causes of OME, including: evidence for and against OME as an allergic disease 2) allergy as a cause for Eustachian tube (ET) obstruction 3) examination of the most sensitive diagnostic tests for allergy and 4) the evidence demonstrating that immunotherapy treatment of underlying allergies leads to resolution of chronic middle ear disease.

top of page

Publication History

Cite this article as

Corresponding author e-mail