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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery
Indexed/Abstracted in: EMBASE, Scopus
INTRATYMPANIC THERAPIES FOR INNER EAR DISORDERS
Otorinolaringologia 2010 September;60(3):189-93
Management of Menière’s disease with intratympanic steroids
Pistorio V., Achilli V.
Division of Otolaryngology Ospedale Maggiore, Lodi, Italy
We made a review of the english-language literature to evaluate the efficiency, optimum dosage and administration schedule of intratympanic corticosteroid therapy in Menière’s disease patients as an alternative to more aggressive therapies, given the evidence that in many cases the underlying etiology and pathophisiology is inflammatory. Results of the up to now published studies are difficult to interpret in that none of them completely meets the requirements of a clinical drug study. For this reason, even if a certain efficacy of intratympanic corticosteroid administration is likely, further investigations are required with controlled, randomised, double-blind trials to get more precise data.