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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery
Indexed/Abstracted in: EMBASE, Scopus
REVIEWS HOT TOPICS IN OTOLARYNGOLOGY
Otorinolaringologia 2010 June;60(2):93-100
Stem cell therapies for laryngeal tissue engineering: a review
McRae B. R., Halum S. L.
Department of Otolaryngology, Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
Emerging stem cell therapies and tissue engineering strategies hold great promise for treating laryngeal injuries and disease. Many conditions that previously lacked effective interventional options may soon be treatable via stem cell-based therapies. Contemporary research includes progress in developing injectable stem cells and other cellular strategies for treatment of vocal fold scar; scaffold-based stem cell systems for engineering vocal fold replacement tissues; the use of stem cells as vectors for delivering intralaryngeal gene therapy; and adaptations within laryngeal tissue transplantation research.