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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery

Indexed/Abstracted in: EMBASE, Scopus




Otorinolaringologia 2007 December;57(4):219-21

language: English

Abrikossoff’s tumour of the tongue: a pediatric case report

Gargano R., Gallina S., Polizzi V., Restivo G., Speciale R.

Department of Othorinolaringology University of Palermo, Palermo, Italy


This case describes an uncommon benign neoplasm named Abrikossoff’s tumour, or granular cell tumour (GCT), in the form of a single, well-circumscribed nodule, which is found predominantly in the head and neck region. More than a half of the head and neck GCTs originate from the tongue, like in this case. It develops between the second and sixth decades of life, more frequently among women and blacks. Histologically, GCT shows numerous strands of large polyhedral granular cells, separated by collagen bundles, with no evidence of encapsulation. Its real etiopathogenesis remains still controversial, apparently arises from neural or Schwann cell origin, with benign and malignant forms. The only treatment for Abrikossoff ‘s tumor is surgery supported by a close follow-up. In this article we report the case of a 9-year old child, presenting a non-painful nodule located in his tongue. The histopathologic study of the specimens, supported by immunohistochemical techniques, determined the lesions to be a GCT. He was treated by excisional resection with radiofrequency. After 12 months he had not suffered any recurrences.

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