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OTORINOLARINGOLOGIA

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Otorinolaringologia 2004 December;54(4):199-201

language: English

Anaplastic large cell lymphoma of maxillary antrum. A case report

Chatterjee T. 1, Singh D. 2, Goyal H. 2, Pautu J. L. 2, Chowdhary G. S. 2, Saxena R. 1

1 Depart­ment of Hem­a­tology All ­India Insti­tute of Med­ical Sci­ences New ­Delhi, ­India
2 Depart­ment of Med­ical ­Oncology All ­India Insti­tute of Med­ical Sci­ences New ­Delhi, ­India


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Ana­plastic ­large ­cell lym­phoma (­ALCL) is rec­og­nized as a dis­tinct sub­type of non-­Hodgkin’s lym­phoma in the ­Revised Euro­pean Amer­ican Lym­phoma (­REAL) clas­sifi­ca­tion. Immu­no­phen­o­typ­i­cally it is ­either T-­cell or ­null ­cell ­type ­along ­with ­almost uni­versal expres­sion of CD30+. Sin­o­nasal ­tract is a ­rare ­site. We ­have ­seen a 50-­year-old ­female who pre­sented ­with a ­mass in the ­right max­il­lary ­antrum and ­nasal ­cavity. ­Initially she was mis­di­ag­nosed as ­poorly dif­fer­en­tiated car­ci­noma and under­went max­il­lec­tomy. But his­top­a­thology of the ­resected spec­imen ­revealed the diag­nosis of ­ALCL ­based on the ­light micro­scopic and immu­no­his­to­chem­ical fea­tures. She ­received ­CHOP chem­o­therapy and con­tinues to ­show com­plete remis­sion at 18 ­months ­follow-up. The pos­sibility of ­ALCL ­should be con­sid­ered in the dif­fe­ren­tial diag­nosis of undif­fer­en­tiated ­tumors of the sin­o­nasal ­tract as sur­gery can be ­avoided if a ­proper diag­nosis is ­made.

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