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Indexed/Abstracted in: EMBASE, Scopus
Online ISSN 1827-188X
Bentz B. G. 1, Kraus D. H. 2
1 Department of Surgery Division of Otolaryngology-Head and Neck Surgery University of Utah, School of Medicine Huntsman Cancer Institute, Salt Lake City, UT, USA
2 Department of Surgery, Head and Neck Service, Memorial Sloan-Kettering Cancer Center New York, NY, USA
The introduction of chemotherapy to the treatment armamentarium for head and neck cancer (H&NCa) has brought about revolutionary changes in the way that we approach advanced head and neck neoplastic disease. Yet, a lack of prospective randomized data to definitively prove survival or functional benefit with the use of these new treatment paradigms underscores the fact that surgical therapy with appropriate reconstruction continues to play a central role in the treatment of advanced stage H&NCa. Because of this rapid evolution of therapeutic strategies, an individual treatment’s role and its interrelationship with other modalities must be constantly reevaluated in order to tailor the most optimal treatment approach to a given clinical problem. The purpose of this review article is to discuss the present state of art for surgical extirpation and reconstruction for advanced neoplastic diseases of the head and neck. These treatment options must continue to be considered mainstay therapy for these patients until the controversies of optimal treatment strategies are adequately resolved.