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Indexed/Abstracted in: EMBASE, Scopus
Online ISSN 1827-188X
Teclu A., Lacroix J. S.
Department of Otorhinolaryngology and Cervico-Facial Surgery University Hospital, Geneva, Switzerland
Chronic rhinosinusitis (CRS) is an inflammatory disease of the nasal and paranasal sinuses mucosa, with symptoms such as nasal obstruction, rhinorrhea and headache, lasting for more than 3 months. Prevalence of CRS has increased during the last 30 years and became the most common chronic disease in industrialised countries affecting about 15% of the population. Nasal polyposis (NP) is considered as the ultimate stage of CRS. The aetiology of CRS is most likely multifactorial including specific and non specific hyperreactivity mechanisms and with different, as yet not well defined predisposing factors. Here the aim is to present a review of the current literature on epidemiology, etiology, histology and therapeutic management of CRS with NP. Since there is no single medical or surgical therapy excluding recurrence of the disease, different approches should be considered.