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OTORINOLARINGOLOGIA

A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery


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Otorinolaringologia 2003 September;53(3):89-97

language: English

Chronic rhinosinusitis and nasal polyposis. A review

Teclu A., Lacroix J. S.

Department of Otorhinolaryngology and Cervico-Facial Surgery University Hospital, Geneva, Switzerland


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Chronic rhin­o­sin­u­sitis (CRS) is an inflam­ma­to­ry dis­ease of the ­nasal and par­a­na­sal sinus­es muco­sa, ­with symp­toms ­such as ­nasal obstruc­tion, rhi­nor­rhea and head­ache, last­ing for ­more ­than 3 ­months. Prevalence of CRS has ­increased dur­ing the ­last 30 ­years and ­became the ­most com­mon chron­ic dis­ease in indus­tri­al­ised coun­tries affect­ing ­about 15% of the pop­u­la­tion. Nasal poly­po­sis (NP) is con­sid­ered as the ulti­mate ­stage of CRS. The aetio­lo­gy of CRS is ­most like­ly mul­ti­fac­to­ri­al includ­ing spe­cif­ic and non spe­cif­ic hyper­reac­tiv­ity mech­a­nisms and ­with dif­fer­ent, as yet not ­well ­defined pre­dis­pos­ing fac­tors. Here the aim is to ­present a ­review of the cur­rent lit­er­a­ture on epi­dem­i­ol­o­gy, eti­ol­o­gy, his­tol­o­gy and ther­a­peu­tic man­age­ment of CRS ­with NP. Since ­there is no sin­gle med­i­cal or sur­gi­cal ther­a­py exclud­ing recur­rence of the dis­ease, dif­fer­ent approch­es ­should be con­sid­ered.

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