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Home > Journals > Otorinolaringologia > Past Issues > Otorinolaringologia 2002 September;52(3) > Otorinolaringologia 2002 September;52(3):121-5



A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery

Indexed/Abstracted in: EMBASE, Scopus

Frequency: Quarterly

ISSN 0026-4938

Online ISSN 1827-188X


Otorinolaringologia 2002 September;52(3):121-5


Madelung’s disease. Case report with cervical involvement

Moretti A., Chiri Z. M., D’Agostino L., Croce A.

Sezione di Otorinolaringoiatria Dipartimento di Scienze Chirurgiche Sperimentali e Cliniche Università degli Studi «G. d’Annunzio», Chieti

­Madelung’s or Lau­nois-Ben­saude’s dis­ease, ­also ­known as ­benign sym­metric lip­o­mat­osis, is a ­rare clin­ical con­di­tion char­ac­ter­ized by mul­tiple and non­en­cap­su­lated adi­pose ­tissue ­deposits local­ized spe­cially in the cer­vical ­region and the ­upper ­back (­Type I). Accu­mu­la­tion of fat has ­also ­been ­described in the abdom­inal ­wall, ­lower ­limbs and ­lumbar ­region (­Type II). ­This dis­ease nor­mally ­affects men ­aged 35-50 ­years and ­there is a ­strong asso­ci­a­tion ­with ­alcohol ­abuse. The eti­ology is ­unknown, but it is fre­quently asso­ciated ­with sev­eral dis­eases: dia­betes mel­litus, hyper­lip­i­demia, ­liver dis­ease, hypo­thy­roidism and poly­neu­rop­athy. ­Over the ­years the fat ­deposits ­achieve a ­large ­size infil­trating the ­nearby struc­tures. ­This ­causes aes­thetic and func­tional prob­lems. ­There is no ­report of spon­ta­neous regres­sion. The ­only effec­tive ­therapy is sur­gical exci­sion of the ­mass. Lip­o­suc­tion can be per­formed in ­patients ­with ­masses of lim­ited ­size and ­when ­there are anes­the­sio­log­ical prob­lems. The dis­ease may ­relapse. The ­authors ­describe a ­case of ­benign sym­metric lip­o­mat­osis ­with cer­vical local­iza­tion. The etio­path­o­gen­esis and treat­ment of ­this dis­ease are dis­cussed.

language: Italian


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