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Indexed/Abstracted in: EMBASE, Scopus
Online ISSN 1827-188X
Noto R., La Mantia I. *, Mirabella C., Messina A. *, Noto P., Serra A. *
From the Università degli Studi - Catania Dipartimento di Medicina Interna e Patologie Sistemiche
*Istituto di Otorinolaringoiatria
Destructive diseases of the mid-face show various etiopathogenesis, some of them sometimes showing symptoms of systemic diseases that have complex diagnoses which make a specific therapy necessary. The authors describe a case of Stewart’s granuloma, a rare and aggressive disease which greatly destroys the structures of the central-face with a serious prognosis making medicinal and surgical therapy difficult. The authors examine the etiopathogenesis hypothesis of these diseases, which is still not well-known and describe the diagnosis which allows us to differentiate the other forms already known, for example Wegener’s granulomatosis. Immuno-histochemical, histo-morphological and immunological data are important for the precise diagnosis in these cases.