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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery
Indexed/Abstracted in: EMBASE, Scopus
Otorinolaringologia 1999 September;49(3):119-24
Post-surgical recurrences of nasal polyps: study of prognostic factors by multivariate analysis
Bussi M., Majore L., Riontino E., Cardarelli L., Ragona R.*, Cortesina G.
Università degli Studi - Torino Dipartimento di Fisiopatologia Clinica Sezione ORL II
* Dipartimento di Discipline Medico-Chirurgiche Sezione Scienze Radiologiche
Background. In the last few years a great number of histopathological, immunohistochemical and immunological studies on nasal polyps have been carried out by several authors in order to investigate the possible factors involved in the etiology as well as in the recurrence of polyposis. Many data suggest that the presence of polyps is the result of various inflammatory, allergic and pseudo-allergic processes which finally lead to the formation of the edema contituting the polyps itself. However, the recurrent nasal polyposis is one of the most common unsolved problem in clinical rhinology.
Methods. In the present study a multivariate analysis on 13 prognostic factors possibly involved in the pathogenesis of post-surgical recurrences was carried out on 50 patients who underwent surgical treatment for nasal polyps at the 2nd ENT Department, University of Turin.
Results and conclusions. With a mean follow-up of 24 months 4/13 of the examined factors (i.e. bilateral polyposis, involvments of different sites, presence of ASA syndrome and eosinopils in the chorion) showed a significant negative impact on recurrence. Findings are presented and discussed.