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A Journal on Otorhinolaryngology, Head and Neck Surgery,
Plastic Reconstructive Surgery, Otoneurosurgery
Indexed/Abstracted in: EMBASE, Scopus
Otorinolaringologia 1999 June;49(2):69-73
Fluid overloads as a possible cause of Ménière’s disease. Clinical review on 27 cases
Albera R., Cavalot A. L., Ferreo V., Lacilla M., Schenone G., Giordano L., Magnano M.*
Università degli Studi - Torino Dipartimento di Fisiopatologia Clinica II Clinica ORL
* Ospedale Mauriziano Umberto I - Torino UOA ORL
Background. Since a study on a significant number of patients with Ménière’s disease is not available, personal experience is reported.
Methods. Twenty-seven cases of Ménière’s disease associated with fluid overload in the diet are reported. In 5 cases fluid overload was acute, i.e. more than 1 liter in few minutes, and in 22 cases chronic, i.e. normal introduction of more than 2 liter each day for more than 1 month. This group of patients represents the 10% of all cases of Ménière’s disease observed in the same period. Vestibular tests showed a unilateral peripheral deficit in 14 cases while each patient was affected by a low frequency neurosensorial hearing loss; in 2 cases hearing loss was bilateral. Therapy consisted in the reduction of fluid overload only.
Results. Vertigo improved in 82% of cases who reported chronic fluid overload and in 100% of cases who reported acute fluid overload; hearing loss improved respectively in 64% and 80% of cases.
Conclusions. Since ADH controls endolymph production, it is possible that fluid overload, reducing ADH concentration, could determine endolymphatic hydrops.