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CURRENT ISSUETHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Journal on Nuclear Medicine and Molecular Imaging

A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
Impact Factor 2,413

Frequency: Quarterly

ISSN 1824-4785

Online ISSN 1827-1936

 

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2015 Jun 23

Prognostic value of Positron Emission Tomography/Computed Tomography in patients with lymphoma treated with autologous stem cell transplantation (ASCT) for relapsed/refractory or high risk disease

Stefani P. M. 1, Salvadori U. 1, Gottardi M. 1, Bissoli S. 2, Chierichetti F. 2, Gherlinzoni F. 1

1 Hematology Unit, General Hospital Hospital, Treviso;
2 Nuclear Medicine Unit, General Hospital, Castelfranco Veneto

AIM: Positron Emission Tomography/Computed Tomography (PET/CT scan) has increasingly been used for management of lymphoma, however few and conflicting data have been provided in the setting of high dose therapy with autologous stem cell transplantation (ASCT) so far.
METHODS: We retrospectively evaluated the outcome of 47 NHL patients who underwent ASCT for relapsed/refractory disease or high risk disease or partial response after first line treatment, with the aim of testing sensitivity, specificity, positive and negative prognostic value of PET/CT performed before and after ASCT.
RESULTS: In our experience pre ASCT-PET/CT predicts outcome of Non Hodgkin’s Lymphoma patients with chemosensitive relapse, whereas post ASCT-PET showed a better prognostic value for relapsed disease.
CONCLUSIONS: Results of our study, if confirmed by studies on a larger scale, could significantly contribute to design future trials and optimise the management of lymphoma patients.

language: English


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