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CURRENT ISSUETHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Journal on Nuclear Medicine and Molecular Imaging


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
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The Quarterly Journal of Nuclear Medicine 2002 March;46(1):24-34

TECHNOLOGIES AND METHODS IN NUCLEAR MEDICINE
Guest Editors: Todd-Pokropek A., Gilardi M. C. 

Dual-modality PET/CT tomography for clinical oncology

Beyer T., Townsend D. W. *, Blodgett T. M. *

From the CPS, Knox­ville, TN, USA
* PET ­Facility, Depart­ment of ­Radiology, Uni­ver­sity of Pitts­burgh Med­ical ­Center, Pitts­burgh, PA, USA

Diag­nosis and ­follow-up in clin­ical ­oncology are tra­di­tion­ally ­based on com­puted tomog­raphy (CT). In ­recent ­years, how­ever, func­tional ­imaging ­using posi­tron emis­sion tomog­raphy (PET) has ­been rec­og­nized as an impor­tant ­imaging ­modality and ­adjunct to CT ­that pro­vides com­ple­men­tary meta­bolic infor­ma­tion in ­many ­oncology appli­ca­tions. To over­come the chal­lenges of ­aligning inde­pen­dently ­acquired PET and CT ­image ­sets sev­eral ad hoc con­cepts of inte­grating PET and CT ­imaging in a ­single ­device ­have ­been pro­posed. ­This ­article com­ments on the devel­op­ment of the ­first com­bined ­dual-­modality PET/CT pro­to­type at the Uni­ver­sity of Pitts­burgh, and illus­trates com­mer­cial ­advances to ­dual-­modality PET/CT tomog­raphy. The cur­rent PET/CT ­designs ­from the ­major man­u­fac­turers com­prise a com­mer­cial CT ­scanner in ­tandem ­with a com­mer­cial PET ­scanner. ­While the ­level of phys­ical inte­gra­tion is actu­ally ­less ­than ­that of the orig­inal pro­to­type it is ­fair to ­assume ­that cur­rent PET/CT ­models may ­serve as inter­mediate solu­tions ­towards ­near-­future ­design con­cepts ­that aim at ­greatly ­reduced ­costs of the ­dual-­modality tom­o­graphs and ­offer a ­greater ­level of phys­ical inte­gra­tion. The ­goal of the ­next gen­er­a­tion of PET/CT ­systems is to ­design and ­build a ­device spe­cif­i­cally for ­imaging the func­tion and ­anatomy of ­cancer in the ­most infor­ma­tive and effec­tive way ­without nec­es­sarily con­cep­tu­al­izing it as com­bined PET and CT scan­ners. ­Such a con­cept of a diag­nostic ­imaging ­device ­relates ­more to a dis­ease man­age­ment ­approach ­rather ­than the ­usual divi­sion ­into med­ical spe­cial­ities ­such as ­radiology and ­nuclear med­i­cine.

language: English


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