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CURRENT ISSUETHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Journal on Nuclear Medicine and Molecular Imaging

A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
Impact Factor 2,413

Frequency: Quarterly

ISSN 1824-4785

Online ISSN 1827-1936

 

The Quarterly Journal of Nuclear Medicine 2002 March;46(1):16-23

TECHNOLOGIES AND METHODS IN NUCLEAR MEDICINE
Guest Editors: Todd-Pokropek A., Gilardi M. C. 

Design considerations for PET scanners

Muehllrhner G., Karp J. S.*, Surti S.*

From ­ADAC UGM, Philadelphia, PA, USA
* University of Pennsylvania, Philadelphia, PA, USA

In 2-D PET scan­ners employ­ing sep­ta, scat­tered radi­a­tion is ­reduced by the sep­ta, plac­ing ­less impor­tance on ­good ener­gy res­o­lu­tion. Additionally, the ­reduced sen­si­tiv­ity in 2-D lim­its the max­i­mum coun­trates encoun­tered in clin­i­cal FDG stud­ies. In con­trast, 3-D PET scan­ners ­rely on ­good ener­gy res­o­lu­tion to ­reduce the scat­tered radi­a­tion and ­also ­must ­deal ­with coun­trates, ­which are typ­i­cal­ly 5 ­times high­er ­than in 2-D ­mode. To ­achieve ­good ener­gy res­o­lu­tion, 3 fac­tors ­must be con­sid­ered: 1) ­choice of a scin­til­la­tor ­with ­good intrin­sic ener­gy res­o­lu­tion, 2) ­choice of a crys­tal dimen­sion ­which trans­mits a uni­form ­amount of ­light to the PMT in ­order to ­avoid ­light ­loss ­along the ­length of the crys­tal and 3) ­choice of a crys­tal-to-PMT ­coupling ­which col­lects a uni­form ­amount of ­light ­from all crys­tals. As PET scan­ners are ­being ­designed ­using new, fast­er scin­til­la­tors for 3-D imag­ing, the appro­pri­ate ­trade-off ­between ener­gy res­o­lu­tion and coun­trate capa­bil­ity ­must be ­found to ­give the ­best over­all ­system per­for­mance. An exam­ple of a ful­ly 3-D PET scan­ner is the Allegro (­ADAC Laboratories), ­which ­uses GSO as the detec­tor mate­ri­al. Given the ­right ­choice of mate­ri­al and ­design param­e­ters, ­good qual­ity, ­high con­trast imag­es can be ­obtained in 3-D in a rel­a­tive­ly ­short ­time.

language: English


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