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CURRENT ISSUETHE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Journal on Nuclear Medicine and Molecular Imaging


A Journal on Nuclear Medicine and Molecular Imaging
Affiliated to the Society of Radiopharmaceutical Sciences and to the International Research Group of Immunoscintigraphy
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index (SciSearch), Scopus
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The Quarterly Journal of Nuclear Medicine 1998 September;42(3):158-65

NEU­RO­PHAR­MA­COL­O­GY 

 ORIGINAL ARTICLES

Spe­cial ­issues in quan­ti­ta­tion of ­brain recep­tors and ­related ­markers by emis­sion com­puted tomog­raphy

Links J. M.

From the ­Radiology and ­Radiological Sci­ence Johns Hop­kins Uni­ver­sity, Bal­ti­more, MD, USA

Emis­sion com­puted tomog­raphy pro­vides an oppor­tu­nity to quan­tify neu­ro­trans­mitter-neu­ro­re­ceptor ­systems in ­vivo. In ­order to do so, ­very ­high ­image ­quality and quan­ti­ta­tive accu­racy are ­required. Quan­ti­ta­tion of ­receptor ­systems ­involves con­sid­er­a­tions of phys­ical ­effects (­such as ­finite spa­tial res­o­lu­tion, ­scatter, and atten­u­a­tion), instru­men­ta­tion ­design (­such as spa­tial sam­pling), ­image pro­cessing (­such as fil­tering), and ­data anal­ysis (­such as ­kinetic mod­eling). Appro­priate appli­ca­tion of ­these con­sid­er­a­tions can ­lead to ­useful ­results, but ­emerging ­approaches ­promise ­even ­greater ­levels of accu­racy and pre­ci­sion.

language: English


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