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Indexed/Abstracted in: e-psyche, EMBASE, PubMed/MEDLINE, Neuroscience Citation Index, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,651
Online ISSN 1827-1855
Rodríguez-Nuñez A. 1, Somoza-Martín M. 1, Gómez-Lado C. 1, Eirís-Puñal J. 1, Camiña-Darriba F. 1, Rodríguez-Segade S. 2, Castro-Gago M. 1
1 Department of Pediatrics Neuropediatric Service University Hospital Santiago de Compostela, Spain
2 Department of Biochemistry and Molecular Biology Santiago de Compostela University Santiago de Compostela, Spain
Aim. The aim of this study was to evaluate the usefulness of cerebral blood flow velocity in the middle cerebral artery measured by transcranial Doppler as criteria to therapeutic action in communicating hydrocephalic children.
Methods. In eight non-tumoral communicating hydrocephalic infants, ranging from five to 18 months of age, monitored from 18 to 36 months (mean time of follow-up: 24.25 months), cerebrospinal fluid (CSF) oxypurines (hypoxanthine and xanthine) and uric acid levels were compared by means of the Evans’ index, the mean weekly increase in cranial circumference, and the transcranial Doppler measurements.
Results. Results indicate that clinical (mean weekly increase in head circumference), radiological (Evans’ index), biochemical (oxypurines and uric acid in the CSF), and hemodynamic (transcranial Doppler) criteria have the same role in monitoring infantile hydrocephalus.
Conclusion. In conclusion the transcranial Doppler measurement can be done noninvasively and examinations can be repeated when needed, obtaining immediate results. Hence, it is the most adequate monitoring technique in clinical practice.