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A Journal on Neurosurgery

Indexed/Abstracted in: e-psyche, EMBASE, PubMed/MEDLINE, Neuroscience Citation Index, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,651

Frequency: Bi-Monthly

ISSN 0390-5616

Online ISSN 1827-1855


Journal of Neurosurgical Sciences 2008 March;52(1):17-21


Therapeutic criteria in communicating childhood hydrocephalus

Rodríguez-Nuñez A. 1, Somoza-Martín M. 1, Gómez-Lado C. 1, Eirís-Puñal J. 1, Camiña-Darriba F. 1, Rodríguez-Segade S. 2, Castro-Gago M. 1

1 Department of Pediatrics Neuropediatric Service University Hospital Santiago de Compostela, Spain
2 Department of Biochemistry and Molecular Biology Santiago de Compostela University Santiago de Compostela, Spain

Aim. The aim of this study was to evaluate the usefulness of cerebral blood flow velocity in the middle cerebral artery measured by transcranial Doppler as criteria to therapeutic action in communicating hydrocephalic children.
Methods. In eight non-tumoral communicating hydrocephalic infants, ranging from five to 18 months of age, monitored from 18 to 36 months (mean time of follow-up: 24.25 months), cerebrospinal fluid (CSF) oxypurines (hypoxanthine and xanthine) and uric acid levels were compared by means of the Evans’ index, the mean weekly increase in cranial circumference, and the transcranial Doppler measurements.
Results. Results indicate that clinical (mean weekly increase in head circumference), radiological (Evans’ index), biochemical (oxypurines and uric acid in the CSF), and hemodynamic (transcranial Doppler) criteria have the same role in monitoring infantile hydrocephalus.
Conclusion. In conclusion the transcranial Doppler measurement can be done noninvasively and examinations can be repeated when needed, obtaining immediate results. Hence, it is the most adequate monitoring technique in clinical practice.

language: English


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