Home > Journals > Journal of Neurosurgical Sciences > Past Issues > Journal of Neurosurgical Sciences 2004 September;48(3) > Journal of Neurosurgical Sciences 2004 September;48(3):129-33

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

JOURNAL OF NEUROSURGICAL SCIENCES

A Journal on Neurosurgery


Indexed/Abstracted in: e-psyche, EMBASE, PubMed/MEDLINE, Neuroscience Citation Index, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,651


eTOC

 

CASE REPORTS  


Journal of Neurosurgical Sciences 2004 September;48(3):129-33

Copyright © 2005 EDIZIONI MINERVA MEDICA

language: English

Multiple sclerosis and gliomas. Clinical remarks on 10 cases and critical review of the literature

Isidori A., Caroli E., Frati A., D’Andrea G., Brogna C., Piccirilli M., Salvati M.

Department of Neurosurgery, INM Neuromed IRCCS Pozzilli (Isernia), Italy


PDF  


The association between multiple sclerosis and tumours of the central nervous system is unusual. The Aauthors analyzed the clinico-pathological elements of the correlation. The pertinent literature on this subject is critically reviewed.
Ten cases of patients with an history of multiple sclerosis for more than 15 years and a clinical and radiological evidence of brain tumour were submitted to surgery in order to remove the lesion and/or to chemo- and radiotherapy. The various aspects of the association were studied in detail.
A patient with multiple sclerosis, particularly with atypical symptoms, should be evaluated by an annual MRI investigation with intravenous paramagnetic contrast medium. The diagnostic work-up should be: clinical and radiological assessment; MRI in the event of atypical symptoms; Sstereotactic or neuronavigation-aided biopsy in any suspected lesions. Patients with multiple sclerosis and glioma present survival times identical to those observed in patients not suffering from multiple sclerosis.
The coexistence of multiple sclerosis and brain tumours does not seem to influence the clinical evolution of either of these pathologies. We believe that it is important to achieve an early diagnosis of brain tumour in such patients with a clinical and neuroradiological follow up, so that they can be treated promptly.

top of page

Publication History

Cite this article as

Corresponding author e-mail