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Journal of Neurosurgical Sciences 2002 June;46(2):96-9

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: English

Ossification of the ligamentum flavum in a Caucasian. Case report

Celli P., Caroli E., Trillò G., Ferrante L.

Department of Neurosurgical Sciences, 2nd Chair of Neurosurgery, Policlinico Umberto I, University of Rome “La Sapienza”, Rome


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There ­have ­been few ­reports of ossifi­ca­tion of the yel­low lig­a­ments caus­ing spi­nal ­cord com­pres­sion in Caucasian pop­u­la­tion. This dis­ease is ­described main­ly in Japanese ­patients and is ­termed as “Japanese dis­ease”. We ­describe the ­case of a 58-­year-old Caucasian ­male ­with pro­gres­sive par­a­par­e­sis. Radiographic fea­tures ­were sug­ges­tive of ossifi­ca­tion of the yel­low lig­a­ments in the low­er tho­rac­ic lev­el caus­ing spi­nal ­cord com­pres­sion. Early decom­pres­sive lam­i­nec­to­my and remov­al of the ossi­fied lig­a­ment result­ed in a ­marked clin­i­cal improve­ment. The etio­log­ical hypoth­e­sis, epi­dem­i­olog­i­cal, his­to­log­i­cal, clin­i­cal and radio­log­i­cal fea­tures of ­this dis­ease are ­reviewed.

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