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MINERVA UROLOGICA E NEFROLOGICA

A Journal on Nephrology and Urology


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  ACUTE KIDNEY INJURY


Minerva Urologica e Nefrologica 2009 September;61(3):189-204

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: English

Renal replacement therapy for acute renal failure

Macedo E., Bouchard J., Mehta R. L.

Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego,San Diego, CA, USA


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Renal replacement therapy became a common clinical tool to treat patients with severe acute kidney injury (AKI) since the 1960s. During this time dialytic options have expanded considerably; biocompatible membranes, bicarbonate dialysate and dialysis machines with volumetric ultrafiltration control have improved the treatment for acute kidney injury. Along with advances in methods of intermittent hemodialysis, continuous renal replacement therapies have gained widespread acceptance in the treatment of dialysis-requiring AKI. However, many of the fundamental aspects of the renal replacement treatment such as indication, timing of dialytic intervention, and choice of dialysis modality are still controversial and may influence AKI patient’s outcomes. This review outlines current concepts in the use of dialysis techniques for AKI and suggests an approach for selecting the optimal method of renal replacement therapy.

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