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A Journal on Nephrology and Urology

Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,536

Frequency: Bi-Monthly

ISSN 0393-2249

Online ISSN 1827-1758


Minerva Urologica e Nefrologica 2004 June;56(2):109-22


Lower urinary tract symptoms and benign prostatic hyperplasia

Skolarikos A. 1, Thorpe A. C. 2, Neal D. E. 3

1 Second Department of Urology University of Athens Sismanoglio Hospital, Athens, Greece
2 Department of Urology Freeman Hospital Newcastle ­upon Tyne, UK
3 Department of Surgery and Cancer Research Oncology Centre Addenbrooke’s Hospital, Cambridge, UK

Benign pros­tat­ic hy­per­pla­sia (BPH) is an im­por­tant ­cause of low­er uri­nary ­tract symp­toms (LUTS). However, ­many oth­er caus­es, in­clud­ing ­smooth mus­cle dys­func­tion and neu­ro­log­i­cal fac­tors may con­trib­ute to ­these symp­toms, and ac­cu­rate di­ag­no­sis is im­per­a­tive be­fore in­va­sive treat­ments are cho­sen. Careful re­cord­ing of symp­toms, giv­ing em­pha­sis on how ­they inter­fere ­with the ­patient’s qual­ity of ­life, as ­well as the use of prop­er­ly se­lect­ed ­tests, con­sti­tutes the main­stay of mak­ing a cor­rect di­ag­no­sis. Men ­with ­mild or mod­er­ate symp­toms not ex­pe­ri­enc­ing com­pli­ca­tions are ­ideal can­di­dates for med­i­cal treat­ment. For the ­rest ­with per­sis­tent symp­toms or com­pli­ca­tions ­such as in­fec­tion, bleed­ing, chron­ic re­ten­tion or re­nal im­pair­ment fur­ther in­ves­ti­ga­tion and ­more in­va­sive ­forms of treat­ment ­need to be con­sid­ered. We re­view the pa­tho-phys­iol­o­gy of the dis­ease, and cur­rent ap­proach­es and man­age­ment of ­this com­mon prob­lem.

language: English


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