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A Journal on Nephrology and Urology

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Minerva Urologica e Nefrologica 2001 March;53(1):33-8

language: Italian

Inflammatory pseudotimor of the urinary bladder. A diagnostic and therapeutic dilemma

Sousa Escandón M. A., Pérez Valcarcel J. *, Cachay Ayala M. E., García Fantini M. **, Garcia Figueiras R. ***, Gonzalez Rodríguez A. ***

Ospedale Comarcale di Monforte - Lugo (Spagna) Reparto di Urologia
*Reparto di Anatomia Patologica
**Reparto di Ginecologia
***Reparto di Radiologia


Inflammatory pseudotumor is a reactive benign lesion which can be very difficult to distinguish from some malignant bladder tumors like sarcomas or sarcomatoid carcinoma. The aim of this study was to present a new case of inflammatory pseudotumor and to review the present diagnostic and terapeutic criteria for this lesion. A 72-year-old female was admitted to the emergency room due to important hematuria. Transurethral resection of a bladder tumor located in the left lateral wall was performed. Pathologic studies were suggestive of inflammatory pseudotumor, but a mixoid leiomyosarcoma couldn’t be completely discarded and a partial cystectomy whith ipsilateral lymphadenectomy were carried out. Immunohistoche-mical studies were positive for vimentin, desmin, smooth muscle actin and cytoqueratins while epithelial membran antigen and S-100 protein were negative. The patient is disease free after a year follow-up. When diagnosis is certain, complete transurethral resection is the treatment of choice. However, if there is no total pathologic confirmation, if it is a very wide lesion or if it is recurring after endoscopic resection, a partial cystectomy is suggested.

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