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MINERVA UROLOGICA E NEFROLOGICA

A Journal on Nephrology and Urology


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  XVI CONGRESS DELLA SOCIETÀ ITALIANA DI NEFROLOGIA SEZIONE PIEMONTE-VALLE D’AOSTA
Castello di Rivoli, Rivoli (TO) October 10, 1998


Minerva Urologica e Nefrologica 2000 September;52(3):143-5

language: Italian

Evaluation of reticulocyte hemoglobin content (CHr) as a guide for iron supplementation in hemodialysed patients

Bosticardo G. M., Arnoletti F. *, Dapiran D. *, Zola P. *, Maneglia M., Avalle U., Giacchino F.

Regione Piemonte - Azienda USL 9 - Ivrea Servizio Nefrologia e Dialisi *Laboratorio Analisi


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Background. In literature the reliability of reticulocyte hemoglobin content (CHr) has been recently emphasized to detect “functional” iron deficiency induced by erythropoietin therapy.
Methods. In the present work the behavior of CHr in 68 uremic patients hemodialysis has been evaluated.
Results. Its values appeared poorly correlated (R2=0.32) to the hypochromic erythrocyte percent values, and furthermore CHr sensitivity seemed poor, with pathologic low values detected in three cases only, all characterized by reduced mean corpuscular volume (MCV).
Conclusions. In the cases personally observed, MCV and CHr are weakly correlated (R2=0.15); reticulocyte hemoglobin absolute value in personal opinion does not appear as a reliable index of iron deficiency, being rather dependent on reticulocyte volume.

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