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MINERVA UROLOGICA E NEFROLOGICA
A Journal on Nephrology and Urology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,536
XV CONGRESS OF THE SOCIETA' ITALIANA DI NEFROLOGIA SEZIONE PIEMONTE-VALLE D'AOSTA
(Verbania, October 4, 1997)
Minerva Urologica e Nefrologica 1999 June;51(2):53-5
Prevalence of anti-HCV antibody positivity and incidence of seroconversion in patients undergoing hemodialysis
Biamino E., Caligaris F., Ferrero S., Montalcini G., Bongiorno P., Scuvera I. *
Regione Piemonte - ASL 19 Asti, Presidio Ospedaliero di Asti, Servizio di Nefrologia e Dialisi
Background and aims. The prevalence of positivity to anti-HCV antibodies and the incidence of seroconversion in a group of patients undergoing replacement hemodialytic treatment was evaluated using a retrospective analysis. The study was carried out in a hemodialysis centre with no areas and/or equipment dedicated to patients positive to anti-HCV antibodies. The aim was to check whether the rigid application of universal aseptic precautions, which are always adopted by the centre, are sufficient to prevent contagion by hepatitis C virus in patients undergoing dialysis.
Methods. The study was carried out in patients receiving dialysis in the Centre (74 patients at the start of the observation period) for two years (7/95-7/97). Anti-HCV antibodies were assayed every two months using a third generation ELISA tests and positive results were confirmed by RIBA III test. At the start of the observation period, 10/74 patients showed positive levels of anti-HCV antibodies (13.5%).
Results. During the period in question none of the patients with negative levels of anti-HCV antibodies at the start of the study became positive. Of the patients undergoing dialysis after 1/7/95, four were already positive for anti-HCV antibodies and none of the others became positive.
Conclusions. The experience confirms that the application of universal aspeptic precautions may be sufficient to prevent the spread of hepatitis C virus in dialysis centres.