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MINERVA UROLOGICA E NEFROLOGICA

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Minerva Urologica e Nefrologica 1999 March;51(1):1-4

language: English

Value of trans­rec­tal ultra­sound in pre­op­er­a­tive stag­ing of pros­tate can­cer

Colombo T., Schips L., Augustin H., Gruber H., Hebel P., Petritsch P.H., Hubmer G.

Universitätsklinik für Urologie, Karl-Franzens-Universität, Graz, Austria


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Background. The aim of the ­study was to com­pare pre­op­er­a­tive trans­rec­tal ultra­sound find­ings ­with fi­nal his­to­path­o­log­i­cal ­stage af­ter rad­i­cal pros­ta­tec­to­my to de­ter­mine the val­ue of ­TRUS in pre­op­er­a­tive stag­ing of pros­tate can­cer.
Methods. The eval­u­a­tion was per­formed as a ret­ro­spec­tive ­study. In 114 rad­i­cal pros­ta­tec­to­my spec­i­mens the his­to­path­o­log­i­cal, ultra­sound and rec­tal dig­i­tal find­ings ­were cor­re­lat­ed. Mean age of pa­tients was 63 ­years and in all pa­tients a rad­i­cal ret­ro­pu­bic pros­ta­tec­to­my was per­formed.
Results. Organ con­fined PC was ­found cor­rect­ly ­with ­TRUS in 68% and cap­su­lar pen­e­tra­tion in 32%. Corresponding find­ings ­with dig­i­tal rec­tal ex­am­ina­tion (DRE) ­were 68% and 17% re­spec­tive­ly. Sensitivity of ­TRUS in or­gan con­fined PC (T1-2) was 66.1% (DRE 68.5%), spec­i­fic­ity 32.6% (DRE 20%) and pos­i­tive pre­dic­tive val­ue 55.7% (DRE 49.3%).
Sensitivity, spec­i­fic­ity and po­sit­ve pre­dic­tive val­ue of ­TRUS for ­stage T3 (a,b,c) ­were 32.6%, 68.4% and 45.5% re­spec­tive­ly. A sep­ar­ate eval­u­a­tion of ­stage T3c re­vealed for ­TRUS: sen­si­tiv­ity 41.2%, spec­i­fic­ity 81.8% and pos­i­tive pre­dic­tive val­ue 36.8%.
Conclusion. On the ba­sis of ­this ret­ro­spec­tive anal­y­sis, and due to the low sen­si­tiv­ity and spec­ti­fic­ity, ­TRUS is not suit­able for ad­e­quate pre­op­er­a­tive stag­ing of pros­tat­ic can­cer.

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