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Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,536
Online ISSN 1827-1758
Aloi F. 1, Solaroli C. 1, Paradiso M. 2, Formiconi A. 2
1 Università degli Studi - Torino, Dipartimento di Discipline Medico Chirurgiche, Sezione di Dermatologia;
2 Ospedale S. Giovanni Battista - Torino, Urologia Ospedaliera
Background. Skin metastasis from transitional cell carcinoma of the urinary bladder is quite uncommon. Especially, the inflammatory type of skin metastasis with features of carcinoma erysipeloides is a rare event.
Case report. A 65-year-old man with bladder carcinoma who underwent radical cystotectomy developed 6 months later red to violaceous papules, indurated plaques and edema in the perigenital area. The initial presumptive diagnosis was irritative contact dermatitis and cellulitis. Histologic examination of a skin biopsy disclosed dilated lymphatic vessels filled with neoplastic cells resembling transitional cells.
Comment. Although carcinoma erypelatoides is most commonly caused by breast carcinoma, it has also been linked to other carcinomas. Dermal lymphatic involvement is an essential feature shared by cases of inflammatory carcinoma.
Conclusions. Carcinoma erysipelatoides may be caused by bladder carcinoma. Skin metastases are generally present in the late stages of this disease and indicate a poor outcome.