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MINERVA UROLOGICA E NEFROLOGICA

A Journal on Nephrology and Urology


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  XIV CONGRESS OF THE SOCIETA' ITALIANA DI NEFROLOGIA SEZIONE PIEMONTE-VALLE D'AOSTA
(Ivrea, October 5, 1996)


Minerva Urologica e Nefrologica 1998 March;50(1):97-100

Copyright © 1998 EDIZIONI MINERVA MEDICA

language: Italian

Response to influenza immunisation in peritoneal dialysis patients

Dogliani M. 1, Fidelio T. 1, Scalzo B. 1, Iacono G. 1, Bagatella M. 2, Piro F. 3

1 USL 6 Ospedale di Ciriè, Servizio di Nefrologia e Dialisi; 2 Assistenza Sanitaria Territoriale; 3 Ospedale Amedeo di Savoia - Torino, Laboratorio di Virologia


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The influenza vaccination is considered useful in preventing influenza and its complications, but its efficacy is variable especially in uremia. The humoral efficacy in a group of 15 patients in peritoneal dialysis treatment has been evaluated. Antibody responses were measured before vaccination and at time intervals of 1-4 months after vaccination. A good response to viruses A (A/H3N2/Johannesburg 33/94, A/H1N1/Sin-gapore 6/86), respectively 80% and 66,7% and an attenuated response (20%) to virus B (B/Beijing 184/93) was observed.
For viruses A, the "non responders" were elder patients with a low count of lymphocytes. For virus B it is suggested that the low response is perhaps related to variable effectiveness of vaccine.

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