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Battista G. 1, Lo Russo L. 1, Padovano Di Leva A. 1, Rubini C. 2, Sberna M. T. 3, Bollero R. 3, De Santis D. 4, D’Agostino A. 4, Bertossi D. 3, Lo Muzio L. 1
1 Department of Clinical Medicine, University of Foggia, Foggia, Italy;
2 Department of Biomedical Sciences, Institute of Pathologic Anatomy, Università Politecnica delle Marche, Ancona, Italy;
3 Department of Dentistry, Vita Salute University San Raffaele Hospital, Milan, Italy;
4 Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy
The authors report a case of oral tuberculosis in a 38-year-old heavy cigarette smoker man. He showed a painful, non-healing ulc er with indurated borders of the lateral surface of the tongue. No tonsil or lymph node enlargement was also noted. The medical history was not significant for systemic disease. Histopathological examination showed granulomas exhibiting a central caseinating necrotic focus, surrounded by mononucl ear cell s, epithelioid histiocytes and multi nucl eated Langhans giant cell s. A mantle of lympocytes and fibrous tissue surrounded the granulomas. Since the morphologic picture oriented for tubercoloid granulomata, a Ziehl- Neelsen staining of the tissue was performed. Chest radiography did not detect any pulmonary or nodal disease. On the bases of these results a diagnosis of oral tuberculosis was establ ished.
language: English, Italian