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A Journal on Dentistry and Maxillofacial Surgery
Minerva Stomatologica 2016 December;65(6):385-92
Platelet-rich fibrin: a boon in regenerative endodontics
Priyanka D. REBENTISH 1, Girish UMASHETTY 2, Harpreet KAUR 3, Trupthi DOIZODE 4, Mithun KASLEKAR 5, Shouvik CHOWDHURY 6 ✉
1 Department of Periodontology, Vasantdada Patil Dental College and Hospital, Kavalapur, India; 2 Department of Conservative Dentistry and Endodontics, Vasantdada Patil Dental College and Hospital, Kavalapur, India; 3 Department of Prosthodontics Including Crown and Bridge, Bhojia Dental College and Hospital, Budh, Baddi, India; 4 Private Practioner, Bangalore, India; 5 Conservative and Dentistry Endodontics, Bangalore Institute of Dental Science, Bangalore, India; 6 Department of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Bareilly, India
Research into regenerative dentistry has contributed momentum to the field of molecular biology. Periapical surgery aims at removing periapical pathology to achieve complete wound healing and regeneration of bone and periodontal tissue. Regenerative endodontic procedures are widely being added to the current armamentarium of pulp therapy procedures. The regenerative potential of platelets has been deliberated. Platelet-rich fibrin (PRF) is a wonderful tissue-engineering product and has recently gained much popularity due its promising results in wound healing bone induction. The features of this product are an attribute of platelets which, after cellular interactions, release growth factors and have shown application in diverse disciplines of dentistry. This paper is intended to shed light onto the various prospects of PRF and to provide clinical insight into regenerative endodontic therapy.