Total amount: € 0,00
HOW TO ORDER
A Journal on Dentistry and Maxillofacial Surgery
Minerva Stomatologica 2016 February;65(1):1-10
Bone regeneration in rat femoral defects after osteotomy with surgical ultrasound
Maria B. BERGONSE PEREIRA PEDRIALI 1, Wilson TREVISAN JUNIOR 1, Fabio GOULART DE ANDRADE 2, João P. MENCK SANGIORGIO 1, William RICARDO PIRES 2, Solange DE PAULA RAMOS 2 ✉
1 Department of Oral Medicine and Pediatric Dentistry, Health Sciences Center, State University of Londrina, Paraná, Brasil; 2 Department of Histology, Biological Sciences Center, State University of Londrina, Paraná, Brasil
To evaluate bone healing after osteotomy by surgical drill (D) and piezoelectric ultrasound (U), Wistar rats were submitted to femoral osteotomy and submitted to histological analysis. After 60 h, slight (83.3%) and moderate (3.4%) inflammatory areas were frequent in the U defects whereas D group presented moderate (33.3%) and severe (16.6%) inflammatory infiltrate (P<0.001). There was few intramedullary hemorrhaging in U (80%) than D group (100%, P<0.05). On the 7th day, inflammatory areas was less frequent in U (30%) than D osteotomies (93.4%) (P<0.005) and D osteotomies presented larger areas of ossification (median: 47%, quartile: 37-64%) than U group (30%, 18.5-38%; P<0.005). After 30 days, ossification was larger in the U defects (65.9±10.1%) than D group (57±14.5%, P<0.05). There was complete bone remodeling in both groups after 60 days. Piezoelectric ultrasound evokes less postoperative inflammatory response, but delay initial bone ossification.