Home > Journals > Minerva Stomatologica > Past Issues > Minerva Stomatologica 2012 April;61(4) > Minerva Stomatologica 2012 April;61(4):101-12





A Journal on Dentistry and Maxillofacial Surgery

Official Journal of the Italian Society of Odontostomatology and Maxillofacial Surgery
Indexed/Abstracted in: CAB, EMBASE, Index to Dental Literature, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index




Minerva Stomatologica 2012 April;61(4):101-12

language: English, Italian

Combined treatment of odontogenic keratocysts: initial marsupialization and successive enucleation with peripheral ostectomy plus Carnoy’s solution application. A five-year follow-up experience

Rossi D. 2, Borgonovo A. E. 1, Vavassori V. 2, Poli P. P. 2, Santoro F. 1

1 School of Oral Surgery, University of Milan, Fondazione IRCCS Ca’Granda Ospedale Maggiore Policlinico, Milan, Italy;
2 Department of Oral Surgery, University of Milan, Dental Clinic, Fondazione IRCCS Ca’Granda Ospedale Maggiore Policlinico, Milan, Italy


AIM: The odontogenic keratocyst (KCOT) is a locally aggressive, cystic jaw lesion with a high growth potential and a propensity for recurrence. Considering its neoplastic features, treatments of keratocysts are required and they are generally classified as conservative or aggressive. However, although in literature there are several studies, the choice of treatment strategies remains controversial. We report a two-stage protocol based on initial marsupialization and successive enucleation.
METHODS:Three cases of large KCOTs have been treated by initial marsupialization and, after a mean period of six months, successive enucleation with peripheral ostectomy and application of Carnoy’s solution was performed.
RESULTS: All patients were instructed in daily irrigation using chlorhexidine 0.2% during the period of marsupialization. After enucleation, good healing was obtained in all cases and from two up to five years of follow-up, there is no evidence of recurrence.
CONCLUSION: Two-stage surgical treatment protocol of keratocyst leads to complete healing, preservation of important anatomical structures and absence of recurrence.

top of page

Publication History

Cite this article as

Corresponding author e-mail