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MINERVA STOMATOLOGICA

A Journal on Dentistry and Maxillofacial Surgery


Official Journal of the Italian Society of Odontostomatology and Maxillofacial Surgery
Indexed/Abstracted in: CAB, EMBASE, Index to Dental Literature, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index


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Minerva Stomatologica 2011 April;60(4):205-16

language: English, Italian

Early bone formation around immediately loaded FBR-coated implants after 8, 10 and 12 weeks: a human histologic evaluation of three retrieved implants

Malchiodi L. 1, Ghensi P. 2, Cucchi A. 3, Trisi P. 4, Szmukler-Moncler S. 5, Corrocher G. 6, Gerosa R. 7

1 Faculty of Medicine, Dentistry and Maxillofacial Surgery Clinic, University of Verona, Verona, Italy;
2 Faculty of Medicine, Dentistry Clinic, University of Milan, Milan, Italy;
3 Faculty of Medicine, Dentistry Clinic, University of Milan, Milan, Italy;
4 Bio.C.R.A (Biomaterials Clinical and Histological Research Association), Scientific Direction;
5 Faculty of Medicine, Department of Stomatology and Maxillofacial Surgery, University of Paris, Paris, France;
6 Oral Surgery Resident, Faculty of Medicine Dentistry Clinic, University of Milan, Milan, Italy;
7 Faculty of Medicine, Dentistry and Maxillofacial Surgery Clinic, University of Verona
Verona, Italy


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The surface characteristics of dental implants play an important role in the osseointegration process. Over the years implant surfaces have been subjected to different treatments, including turning, plasma spraying, coating, sand blasting, acid etching, and anodization. FBR coating is a fully resorbable calcium phosphate (CaP) coating made of brushite, obtained by electrochemical deposition on titanium plasma-sprayed (TPS) implants; this bioactive layer may be totally resorbable in 6-12 weeks and once the FBR coating has been resorbed, the newly formed bone is in contact with the roughness of the TPS surface. Human biopsy of immediately-loaded implants is certainly the most definitive means of determining the occurrence of osseointegration. In this case series the histologic and histomorphometric features of the bone-implant interface are analyzed and discussed in 3 immediately restored implants, retrieved from human subjects at 8, 10 and 12 weeks, respectively. All 3 implants were osseointegrated, with a bone to implant contact (BIC) ranging from 54.4% to 70.1%. The FBR coating was resorbed and replaced by new bone. Osteoconduction was especially noticeable between the implant threads, where the pristine bone was removed during implant bed preparation. The results suggest that the resorption window of 6-12 weeks for the CaP coating seems to be confirmed at least in the human mandible, and that immediately loaded FBR-coated implants placed in the posterior mandible can achieve osseointegration within 6-12 weeks of loading.

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