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MINERVA STOMATOLOGICA

A Journal on Dentistry and Maxillofacial Surgery


Official Journal of the Italian Society of Odontostomatology and Maxillofacial Surgery
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Minerva Stomatologica 2008 September;57(9):447-51

Copyright © 2008 EDIZIONI MINERVA MEDICA

language: English, Italian

Large oral soft tissue metastasis from anaplastic carcinoma of the lung mimicking a primitive malignancy: case report and brief review of the literature

Califano L. 1, Sanguedolce F. 2, Staibano S. 3, Pannone G. 2, Tortorella S. 2, Serpico R. 4, Lo Muzio L. 5, Bufo P. 2

1 Department of Maxillofacial Surgery Federico II University of Naples, Naples, Italy 2 Section of Anatomic Pathology and Cytopathology, Department of Surgical Sciences University of Foggia, Foggia, Italy 3 Department of Biomorphological and Surgical Sciences Federico II University of Naples, Naples, Italy 4 Section of Oral Pathology Department of Orthodontical and Surgical Sciences Second University of Naples, Naples, Italy 5 Department of Surgical Sciences University of Foggia, Foggia, Italy


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Metastatic tumours to the oral region are rare, and those reported in the buccal soft tissues are even less frequent. We describe a case of anaplastic carcinoma of the lung in a 60-year-old man, presenting a huge oral metastasis as the first sign of his primitive lung malignancy. Clinically, the oral lesion mimicked a high-grade primitive carcinoma of the oral cavity. The biopsy established the gingival metastasis from lung cancer which was confirmed by a fine-needle aspiration cytology examination. We report an uncommon case of metastatic lung carcinoma to the gingiva emphasizing the differential diagnosis between primary and metastatic tumours; a short discussion on the pathways of metastatization to oral cavity soft tissues, as well as brief review of the literature are also presented..

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