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A Journal on Dentistry and Maxillofacial Surgery
Minerva Stomatologica 2002 April;51(4):151-6
language: English, Italian
Stevens-Johnson syndrome presumably induced by bromhexine. A case report
Cafasso A., Rao F., Mucciarone L., Ambrosino Di Miccio S.
The Stevens-Johnson syndrome is a serious form of erythema multiforme, an acute inflammatory pathology with an autoimmune pathogenesis. Its etiology is unknown, although it is thought to have multifactorial causes; nonetheless, many drugs are thought to induce such an immune response. The clinical symptomatology is mainly muco-cutaneous, with a remarkable oral involvement. The authors describe here a case of Stevens-Johnson syndrome involving the ocular, oral, and genital areas, presumably induced by the bromhexine administered to the patient for a viral syndrome.