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Minerva Psichiatrica 2012 June;53(2):101-6

language: English

Effects of illness duration and number of psychotic attacks on cognitive and intellectual impairment of schizophrenic patients

Vaziri A. 1, Rezaei O. 2, Dolatshahi B. 3

1 Clinical Psychology Science and Research Branch, Islamic Azad University, Tehran, Iran;
2 Department of Psychiatry, University of Social Welfare and Rehabilitation Science, Tehran, Iran;
3 Department of Psychology, University of Social Welfare and Rehabilitation Science, Tehran, Iran


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Aim. The course of cognitive impairment in schizophrenia is a deteriorative course, in which patients’ cognitive and intellectual deficits worsen progressively throughout the long duration of the illness after an insidious onset, or is a static phenomenon, which means that once they arise, remain relatively stable. The aim of this study was to investigate the effects of the illness duration and the number of psychotic attacks on cognitive and intellectual impairment of patients with schizophrenia
Methods. In this retrospective study 52 schizophrenic male inpatients were evaluated by Wechsler Adult Intelligence Scale-R test and their demographic characteristics were also obtained. Descriptive statistical methods were used. P-value <0.05 was considered statistically significant.
Results. According to our results, cognitive impairment in schizophrenic patients was generally related to illness duration and number of psychotic attacks. Full scale IQ was negatively correlated with illness duration (R2=-0.33, P<0.02) and the number of psychotic attacks (R2=-0.31, P=0.03). Patients had the highest scores in information, vocabulary and comprehension; and the lowest scores in block design, objects assembly and digit symbol. There was a significant correlation between illness duration and arithmetic, picture arrangement, and block design and a significant correlation between number of psychotic attacks and comprehension and similarities.
Conclusion. It can be inferred from the performance of our participants in sub-tests of WAIS-R scale that the aspects of intelligence which are influenced by education and cultural factors are less impaired in schizophrenic patients than other aspects more influenced by biological factors.

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