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A Journal on Psychiatry, Psychology and Psychopharmacology


Official Journal of the Italian Society of Social Psychiatry
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Minerva Psichiatrica 2012 June;53(2):91-100

language: Italian

Cyclothymic temperament in obsessive-compulsive disorder’s patients

D’Ambrosio V., Albert U., Domene Boccolini F., Mirra M., Bogetto F., Maina G.

Servizio per i Disturbi Depressivi e d’Ansia, Dipartimento di Neuroscienze, Università di Torino, Torino, Italia


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AIM: There are several studies valuing bipolar disorder comorbidity in obsessive-compulsive disorder (OCD) but few data analyze soft bipolar forms comorbidity in OCD. Aim of this study is to evaluate affective temperaments in patients with OCD and to analyze differences in socio-demographic and clinical characteristics, with particular attention to drug-induced hypomania, according as the presence or absence of cyclothymic temperament.
METHODS: The sample consisted of 186 patients with a principal diagnosis of OCD (DSM-IV-TR). Socio-demographic and clinical characteristics were recognized for each patient. Affective temperaments were determined through TEMPS-I somministration.
RESULTS: Cyclothymic affective temperament (CT) was the most represented in the sample of OCD patients (18.8%). Patients with DOC and CT, in comparison with patients without CT, showed significantly higher scores at the HAM-D and the HAM-A, more simmetry obsession, higher rates of eating disorders, of obsessive-compulsive spectrum disorders and of Axis II comorbidity (particularly Cluster A) and more drug-induced hypomania (14.3% vs. 1.4%).
CONCLUSION: CT, when observed in OCD patients, appears fundamental to define a severe form of disorder. Patients with OCD and CT may belong to the soft bipolar spectrum, however a systematic assessment of affective temperaments is necessary in OCD patients. A higher prevalence of drug-induced hypomania stimulates future considerations about therapy

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