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A Journal on Psychiatry, Psychology and Psychopharmacology


Official Journal of the Italian Society of Social Psychiatry
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Minerva Psichiatrica 2012 March;53(1):39-46

language: English

Diagnosis and management of psychiatric comorbidities in patients with hyperthyroidism: an updated review

Deneke D. E., Ravindranath D.

Department of Psychiatry, University of Michigan Health System, Ann Arbor, MI, USA


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Hyperthyroidism affects 1-5% of the population. The majority of cases are due to Graves’ disease, while other common causes include toxic multinodular goiter and toxic adenoma. Psychiatric symptoms have been long associated with hyperthyroid disease, but the nature of the association, including prevalence of psychiatric symptoms and diagnoses, remains unclear. Subclinical hyperthyroidism remains a controversial subject in the literature, and has gained more attention in recent years likely due to more sensitive screening assays. Recent literature shows conflicting data regarding the prevalence of psychiatric symptoms, including depression, anxiety, and cognitive impairment, among patients with subclinical hyperthyroidism. This review provides an update of the literature regarding psychiatric symptoms among patients with both overt and subclinical hyperthyroidism over the past ten years through a search of the Pubmed/MEDLINE database. Thyroid screening and treatment among psychiatric populations are also discussed.

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