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Official Journal of the Italian Society of Social Psychiatry
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Minerva Psichiatrica 2001 December;42(4):315-18

language: Italian

Citalopram and methadone association in the treatment of opiate addiction

Savatteri V., Faillace G., Abrignani M.


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Background. Recent theories on the serotonin-dopamine biobalance appear to support the combined use of SSRI-methadone in order to reduce addiction-compulsion phenomena.
Methods. Ten patients were treated in this study using a combined citalopram-methadone protocol with an anti-addictive effect.
Results. Craving was reduced at the end of treatment compared to treatment with methadone alone.
Conclusions. Treatment with methadone alone does not appear to be effective for the complete treatment of opiate-addicted patients.

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