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A Journal on Psychiatry, Psychology and Psychopharmacology
Official Journal of the Italian Society of Social Psychiatry
Indexed/Abstracted in: EMBASE, e-psyche, PsycINFO, Scopus
Minerva Psichiatrica 2001 December;42(4):315-18
Citalopram and methadone association in the treatment of opiate addiction
Savatteri V., Faillace G., Abrignani M.
Background. Recent theories on the serotonin-dopamine biobalance appear to support the combined use of SSRI-methadone in order to reduce addiction-compulsion phenomena.
Methods. Ten patients were treated in this study using a combined citalopram-methadone protocol with an anti-addictive effect.
Results. Craving was reduced at the end of treatment compared to treatment with methadone alone.
Conclusions. Treatment with methadone alone does not appear to be effective for the complete treatment of opiate-addicted patients.