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Minerva Psichiatrica 2001 September;42(3):231-8

language: Italian

Improvement of depression after minor cranial and neck trauma with SSRI citalopram. A clinical study of 30 cases

Fargione G., Zingale A.


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Background. The depression is a common consequence of minor cranial and neck trauma. In this study the effectiveness of citalopram, a SSRI drug in the management of this type of depression, is evaluated.
Methods. Experimental design: a clinical study covering a three months period. Setting: the patients were all outpatients affected by minor cranial and neck post traumatic depression. Patients: 15 males and 15 females with mean age of 37 years old. Intervention: The patients were treated with oral citalopram 20 mg/day for three months and observed clinically with scheduled administration of SASS (Social Adaptation Self-evaluation Scale).
Results. Twernty-eight patients showed good improvement. In two patients the improvement was slight.
Conclusions. The study showed the effectiveness of citalopram in the treatment of posttraumatic depression without severe side effects.

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