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MINERVA PNEUMOLOGICA

A Journal on Diseases of the Respiratory System


Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index


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Minerva Pneumologica 2017 June;56(2):96-106

DOI: 10.23736/S0026-4954.17.01790-4

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Bronchoscopic treatment of emphysema: an update on lung volume reduction coils

Michela BEZZI 1, Sofia ROMANI 1, Dirk-Jan SLEBOS 2

1 Department of Interventional Pulmonology, University Hospital Careggi, Florence, Italy; 2 Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands


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Emphysema is a destructive process of the lung parenchyma characterized by the permanent enlargement of air spaces distal to the terminal bronchioles. Emphysema causes an increase in airflow resistance and pulmonary compliance. The expiratory flow limitation prolongs expiration, and this may also lead to pulmonary hyperinflation. The gold standard approach necessitates a multidisciplinary team so that patients receive comprehensive treatment from rehabilitation through a lung volume reduction intervention that is appropriate for the patient. Lung volume reduction coil (LVRC) is an implantable device for the endoscopic treatment of emphysema. LVRC treatment is a therapy, independent of collateral flow, for patients with both heterogeneous as well as homogeneous emphysema. The efficacy results have shown promising improvements in pulmonary function, exercise capacity and quality of life. LVRC has a good safety profile and has no significant long term adverse events related to the procedure or the device.


KEY WORDS: Emphysema - Pneumonectomy - Bronchoscopy

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Issue published online: May 8, 2017

Cite this article as

Bezzi M, Romani S, Slebos DJ. Bronchoscopic treatment of emphysema: an update on lung volume reduction coils. Minerva Pneumol 2017;56:96-106. DOI: 10.23736/S0026-4954.17.01790-4

Corresponding author e-mail

d.j.slebos@umcg.nl