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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2008 June;47(2):109-19
Renal function after lung transplantation
Esposito C., Esposito V., De Mauri A.
Unit of Nephrology, Dialysis and Transplantation IRCCS San Matteo Polyclinic University of Pavia, Pavia, Italy
The improvement of long-term survival is one of the consequences of the greater success and availability of lung transplantation. However, the increased number of survivors has meant an increased number of complications. Among these complications the most threatening are acute renal injury and chronic kidney disease, which are associated with significant morbidity and mortality. Several studies have addressed this problem in the attempt to identify patients at risk for impairment of renal function. The identification of risk factors and mechanisms leading to renal damage could help preventing renal complications and treating them before end stage renal failure develops. This review will focus on the major causes and mechanisms of renal damage in lung transplantion recipients.