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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2008 June;47(2):53-62
Interstitial lung disease and lung transplantation
Bhorade S. M., Brush D. R.
Division of Pulmonary and Critical Care Medicine University of Chicago Medical Center Chicago, IL, USA
Interstitial lung disease (ILD) comprises a group of heterogenous disorders that may be associated with progressive respiratory failure that eventually results in death. While current medical therapies have been successful in certain patients with ILD, there remains a subset of patients who continue to progress despite these therapies. In these patients, lung transplantation may provide an alternative therapeutic option. This review will discuss the newest developments in the field of lung transplantation and interstitial lung disease. Specifically, this review will discuss the impact of the new donor lung allocation system in the United States on patients with ILD, the most recent International Society of Heart and Lung Transplantation guidelines for selection of lung transplant recipients the types of lung transplant procedure options and outcomes after transplantation. The most common medical complications associated with lung transplantation will also be discussed.