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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
AN UPDATE ON OBSTRUCTIVE SLEEP APNEA SYNDROME
Minerva Pneumologica 2007 September;46(3):183-90
Obesity and obstructive sleep apnea
Kumar S., Kalra M.
1 Division of Pulmonary Medicine Cincinnati Children’s Hospital Cincinnati, OH, USA
2 Department of Pediatrics University of Cincinnati, Cincinnati, OH, USA
During the last few decades there has been a dramatic worldwide increase in the prevalence of obesity. Consequent to this increase, the obesity associated morbidities are steadily rising and have become a major public health concern. One such morbidity is obstructive sleep apnea (OSA). The etiology of OSA is multifactorial, consisting of a complex interplay between factors related to upper airway anatomy and neuromuscular control of upper airway. Obesity can potentially contribute to the pathogenesis of OSA through modification of both these mechanisms. When untreated, OSA is independently associated with neurocognitive deficits and cardiovascular and metabolic sequelae. OSA in itself can therefore perpetuate the degree of obesity further. Early identification and treatment of OSA cannot therefore be overemphasized. Weight loss is an important component in the management of OSA in obese individuals. Because non-operative approaches to weight loss have shown less than optimal results, obese patients, particularly those with severe obesity, are increasingly seeking bariatric surgical intervention.