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Official Journal of the Italian Society of Thoracic Endoscopy
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  AN UPDATE ON OBSTRUCTIVE SLEEP APNEA SYNDROME


Minerva Pneumologica 2007 September;46(3):183-90

Copyright © 2007 EDIZIONI MINERVA MEDICA

language: English

Obesity and obstructive sleep apnea

Kumar S., Kalra M.

1 Division of Pulmonary Medicine Cincinnati Children’s Hospital Cincinnati, OH, USA 2 Department of Pediatrics University of Cincinnati, Cincinnati, OH, USA


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During the last few decades there has been a dramatic worldwide increase in the prevalence of obesity. Consequent to this increase, the obesity associated morbidities are steadily rising and have become a major public health concern. One such morbidity is obstructive sleep apnea (OSA). The etiology of OSA is multifactorial, consisting of a complex interplay between factors related to upper airway anatomy and neuromuscular control of upper airway. Obesity can potentially contribute to the pathogenesis of OSA through modification of both these mechanisms. When untreated, OSA is independently associated with neurocognitive deficits and cardiovascular and metabolic sequelae. OSA in itself can therefore perpetuate the degree of obesity further. Early identification and treatment of OSA cannot therefore be overemphasized. Weight loss is an important component in the management of OSA in obese individuals. Because non-operative approaches to weight loss have shown less than optimal results, obese patients, particularly those with severe obesity, are increasingly seeking bariatric surgical intervention.

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